LYMPHOID NEOPLASIA The tumor suppressor gene WWOX links the canonical and noncanonical NF- B pathways in HTLV-I Tax-mediated tumorigenesis

1University of Pittsburgh Cancer Institute, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, PA; 2Department of Microbiology and Oncology, Graduate School of Medicine, and 3Transdisciplinary Research Organization for Subtropics and Island Studies, University of the Ryukyus, Okinawa, Japan; 4The Lautenberg Center for General and Tumor Immunology, Institute for Medical Research Israel-Canada, Hebrew University–Hadassah Medical School, Jerusalem, Israel; and 5Child Health Institute of New Jersey, Departments of Pediatrics and Molecular Genetics, Microbiology and Immunology, University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, New Brunswick, NJ